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Approximately60% of subjects developed positive antibody responses.Clinical benefits were observed on the Disability Assess-ment for Dementia (DAD), evidenced by a slowingof decline in the treated group at week 84. Two lobes ofthe nucleus and the surrounding cytoplasm arevisible.

Note the direction of blood flow in open and closed circulations, c.Scanning electron micrograph ofthe splenic sinus,showing the architectureofthe sinuswall asseenfrom its luminal side.

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